DiclofenacGel 100 Mg. Voltaren Gel Coupon. Nulla luctus eleifend . Diclofenac was approved for treating swelling, discomfort and temperature in patients with rheumatoid arthritis osteoarthritis, yet it could additionally be considered addressing menstrual cramps in women patients. Learn More. Recent Updates. Dewasa: 1 tablet (50 mg) sebanyak 2 - 3 kali per hari. Anak-anak di atas 1 tahun : 0,5 - 3 mg/kgBB/hari dalam dosis terbagi. Osteoartritis : 2 - 3 kali sehari 50 mg. Reumatoid artritis : 3 - 4 kali sehari 50 mg. Ankilosing spondilitis : 4 kali sehari 25 mg. Aturan Pakai. Diclofenac Sodium dapat dikonsumsi segera sesudah makan. Diclofenacpotassium immediate-release tablets: 50 mg orally 2 or 3 times a day Diclofenac sodium enteric-coated tablets: 50 mg orally 2 or 3 times a day or 75 mg orally 2 times a day Maximum dose: 150 mg daily Diclofenac sodium extended-release tablets: 100 mg orally once a day Use: For the relief of signs and symptoms of osteoarthritis. Usual 1tablet contains diclofenac sodium 50 mg; excipients: lactose monohydrate, microcrystalline cellulose, corn starch, povidone, colloidal anhydrous silica, magnesium stearate; Release form Intestinal soluble tablets. Pharmacological properties Diclofenac sodium-based non-steroidal drug. The main active ingredient of this drug has a pronounced Komposisi Tiap tablet salut enterik mengandung : Diclofenac sodium 50 mg. Cara Penyimpanan. Simpan ditempat sejuk dan terhindar dari sinar matahari langsung. Kemasan. Strip Isi 10 tablet salut enterik. Diproduksi Oleh. PT Dexa Medica. Produksi. RHFBoV0. Diclofenac adalah obat untuk meredakan nyeri dan peradangan. Obat ini dapat meredakan nyeri pada beberapa kondisi, seperti nyeri haid, nyeri pascaoperasi, atau nyeri sendi akibat radang sendi arthritis. Diclofenac merupakan obat antiinflamasi nonsteroid yang bekerja dengan cara menghambat produksi prostaglandin, yaitu zat yang memicu reaksi peradangan saat tubuh mengalami cedera atau luka. Dengan begitu gejala radang, seperti nyeri atau bengkak bisa mereda. Merek dagang diclofenac Aclonac, Cataflam, Clofecon, Diclofenac Potassium, Diclofenac Sodium, Eflagen, Exaflam, Fenavel, Hotin DCL, Kaflam, Lafen, Neuralgin Rhema, Scantaren, Simflamfas, Voltadex, Voltaren, Zelona Apa Itu Diclofenac Golongan Obat resep Kategori Obat antiinflamasi nonsteroid OAINS Manfaat Mengobati nyeri dan peradangan Dikonsumsi oleh Dewasa dan anak-anak Diclofenac untuk ibu hamil dan menyusui Usia kehamilan trimester 1 dan 2 Kategori C Studi pada binatang percobaan memperlihatkan adanya efek samping terhadap janin, tetapi belum ada studi terkontrol pada wanita hamil. Obat hanya boleh digunakan jika besarnya manfaat yang diharapkan melebihi besarnya risiko terhadap janin. Usia kehamilan trimester 3 Kategori D Ada bukti positif mengenai risiko terhadap janin manusia, tetapi besarnya manfaat yang diperoleh mungkin lebih besar dari risikonya, misalnya untuk mengatasi situasi yang mengancam jiwa. Diclofenac dapat terserap ke dalam ASI. Bila Anda sedang menyusui, jangan menggunakan obat ini tanpa berkonsultasi dulu dengan dokter. Bentuk obat Tablet, kapsul, suntik, gel, tetes mata, suppositoria Peringatan Sebelum Menggunakan Diclofenac Ada beberapa hal yang harus Anda perhatikan sebelum menggunakan diclofenac, yaitu Beri tahu dokter tentang riwayat alergi yang Anda miliki. Diclofenac tidak boleh diberikan kepada pasien yang alergi terhadap obat ini, aspirin, atau obat antiinflamasi nonsteroid lain. Beri tahu dokter jika Anda baru menjalani atau berencana untuk melakukan operasi bypass jantung. Diclofenac tidak boleh diberikan pada pasien dengan kondisi tersebut. Beri tahu dokter jika Anda sedang atau pernah menderita asma, penyakit jantung, hipertensi, gangguan pembekuan darah, perdarahan saluran pencernaan, stroke, tukak lambung, edema, atau penyakit ginjal. Beri tahu dokter jika Anda perokok aktif atau mengalami kecanduan alkohol, karena kondisi tersebut bisa meningkatkan risiko terjadinya efek samping. Beri tahu dokter jika Anda sedang hamil, menyusui, atau sedang merencanakan kehamilan. Diclofenac tidak boleh digunakan oleh wanita hamil terutama pada trimester ketiga. Beri tahu dokter jika Anda sedang menggunakan obat, suplemen, atau produk herbal tertentu. Jangan menggunakan OAINS lebih dari 10 hari, kecuali atas saran dari dokter. Segera temui dokter jika Anda mengalami reaksi alergi obat, overdosis, atau efek samping serius setelah menggunakan diclofenac. Dosis dan Aturan Pakai Diclofenac Berikut ini adalah dosis diclofenac berdasarkan bentuk obat, usia pasien, dan kondisi yang akan diatasi Bentuk Tablet Oral Tujuan Meredakan nyeri akut dan peradangan akibat osteoarthritis, rheumatoid arthritis, atau nyeri haid Dewasa Dosisnya 50 mg, 2–3 kali sehari. Anak-anak usia >14 tahun Dosisnya 25 mg 3 kali sehari atau 50 mg 2 kali sehari. Tujuan Meredakan migrain akut Dewasa Dosis awal 50 mg pada serangan pertama. Bila migrain masih terasa setelah 2 jam, konsumsi lagi sebanyak 50 mg. Selama gejala masih ada, konsumsi obat 50 mg tiap 4–6 jam. Dosis maksimal 200 mg per hari. Bentuk Suntik Tujuan Meredakan nyeri kolik ginjal Dewasa Dosisnya 75 mg disuntikkan melalui otot intramuskular/IM, dosis dapat diulang setelah 30 menit jika diperlukan. Dosis maksimal 150 mg per hari. Pengobatan dilakukan maksimal selama 2 hari. Tujuan Meredakan nyeri dan peradangan. Dewasa Dosisnya 75 mg per hari disuntikkan melalui otot intramuskular/IM. Dosis maksimal 150 mg per hari. Pengobatan dilakukan maksimal selama 2 hari. Tujuan Meredakan nyeri pascaoperasi Dewasa Dosisnya 75 mg diberikan melalui infus intravena IV selama 30–120 menit. Dosis dapat diberikan kembali setelah 4–6 jam billa diperlukan. Dosis maksimal 150 mg per hari. Pengobatan maksimal selama 2 hari. Bentuk Gel Tujuan Meredakan nyeri dan peradangan, nyeri otot, nyeri sendi, keseleo,atau osteoarthritis Dewasa Oleskan 2–4 gram pada bagian sendi yang sakit 2–4 kali sehari. Dosis maksimal 8 gram per hari. Lama pengobatan maksimal 7 hari. Bentuk Tetes Mata Tujuan Meredakan nyeri setelah operasi katarak Dewasa Dosisnya 1 tetes ke mata yang nyeri sebanyak 4 kali sehari selama 2 minggu. Pengobatan dimulai 24 jam setelah operasi. Bentuk Suppositoria Tujuan Meredakan nyeri dan peradangan Dewasa Dosisnya 75–150 mg per hari, dibagi menjadi beberapa dosis. Tujuan Meredakan nyeri pada arthritis juvenil kronis pada anak dan remaja Anak-anak usia 1–12 tahun Dosisnya 1–3 mg mg/kgBB per hari, dibagi menjadi 2–3 dosis. Cara Menggunakan Diclofenac dengan Benar Periksakan diri ke dokter jika nyeri tidak kunjung mereda dalam waktu 10 hari setelah penggunaan diclofenac. Selalu ikuti petunjuk dokter dan baca instruksi yang terdapat pada kemasan obat sebelum menggunakan diclofenac. Berikut ini adalah cara menggunakan diclofenac dengan benar, sesuai bentuk obatnya 1. Diclofenac tablet dan kapsul Diclofenac tablet dapat dikonsumsi sebelum atau setelah makan. Untuk mencegah sakit perut, sebaiknya konsumsi diclofenal saat atau setelah makan. Telan diclofenac tablet secara utuh dengan bantuan segelas air putih. Jangan menghancurkan, mengunyah, atau membelah tablet diclofenac. Jangan berbaring setelah mengonsumsi diclofenac tablet, setidaknya sampai 10 menit. 2. Diclofenac suntik Diclofenac suntik akan diberikan oleh dokter atau tenaga kesehatan di bawah pengawasan dokter langsung di rumah sakit. Diclofenac suntik akan disuntikkan melalui pembuluh darah intravena/IV atau melalui otot intramuskular/IM. 3. Diclofenac gel Sebelum menggunakan diclofenac gel, bersihkan bagian yang akan dioleskan obat. Oleskan obat secukupnya pada bagian yang terasa nyeri. Selalu cuci tangan lalu keringkan sebelum dan sesudah menggunakan obat ini. Hindari penggunaan obat pada luka terbuka, kulit yang terkelupas, atau kulit yang terinfeksi. Jangan menggunakan kosmetik atau produk perawatan kulit lain pada bagian yang dioleskan diclofenac. Jangan membilas bagian yang diberi obat setidaknya sampai 1 jam setelah pengaplikasian. Tunggu hingga 10 menit sebelum menutup bagian kulit yang diberikan obat. 4. Diclofenac tetes mata Sebelum menggunakan diclofenac tetes mata, cuci tangan dengan bersih dan keringkan. Pastikan ujung botol tetes mata tidak menyentuh permukaan apa pun. Dongakkan wajah dan tarik kelopak mata bagian bawah, kemudian teteskan 1 tetes obat ke kelopak mata bagian bawah dan tutup mata. Tekan ujung mata dekat hidung selama 1–2 menit. Jangan berkedip atau menggaruk mata sampai obat meresap ke dalam mata. Ulangi langkah di atas bila dosis Anda lebih dari 1 tetes. Bila Anda menggunakan beberapa jenis obat tetes mata secara bersamaan, beri jeda waktu sekitar 5–10 menit sebelum menggunakan tetes mata lainnya. 5. Diclofenac suppositoria Sebelum menggunakan diclofenac suppositoria, cuci tangan dan dubur menggunakan sabun dengan bersih, lalu keringkan. Setelah itu, masukkan obat ke dalam dubur, minimal sedalam 3 cm. Duduk atau berbaring dulu selama 15 menit sampai obat melunak di dalam dubur. Interaksi Diclofenac dengan Obat Lain Beberapa efek interaksi yang bisa terjadi jika diclofenac digunakan bersama obat lain adalah Peningkatan risiko terjadi perdarahan, termasuk perdarahan saluran pencernaan jika digunakan dengan obat antiinflamasi nonsteroid OAINS lain, obat pengencer darah, antidepresan SSRI, atau kortikosteroid Peningkatan risiko terjadinya hiperkalemia, yaitu tingginya kadar kalium di dalam darah, jika digunakan dengan obat diuretik hemat kalium, ciclosporin, maupun tacrolimus Penurunan efektivitas obat ACE inhibitor atau penghambat beta Peningkatan kadar phenytoin, methotrexate, lithium, atau digoxin, di dalam darah Peningkatan konsentrasi diclofenac dalam darah jika digunakan dengan voriconazole atau amiodarone Efek Samping dan Bahaya Diclofenac Ada beberapa efek samping yang bisa terjadi setelah menggunakan diclofenac, di antaranya Sakit perut atau heartburn Mual atau kembung Diare atau sembelit Pusing, kantuk, atau sakit kepala Periksakan diri ke dokter jika efek samping tersebut tidak kunjung reda atau justru bertambah parah. Segera temui dokter jika Anda mengalami reaksi alergi obat atau efek samping yang lebih serius berikut ini Perdarahan saluran cerna, yang ditandai dengan gejala berupa tinja berdarah, sakit perut yang berat, muntah berwarna gelap yang terlihat seperti bubuk kopi Gangguan jantung, yang bisa ditandai dengan bengkak di kaki, napas pendek, atau lelah yang tidak biasa Gangguan ginjal, yang bisa ditandai dengan keluhan jarang berkemih, jumlah urine sangat sedikit, nyeri saat berkemih, atau sulit bernapas Gangguan hati, yang bisa ditandai dengan sakit perut, mual dan muntah yang terus-menerus, gatal, urine berwarna gelap, atau penyakit kuning Generic name diclofenac [ dye-KLOE-fen-ak ] Brand names Cambia, Zipsor, Zorvolex, Cataflam, Voltaren, Voltaren-XR, Dyloject Drug class Nonsteroidal anti-inflammatory drugs Uses Warnings Before taking Dosage Side effects Interactions FAQ What is diclofenac? Diclofenac is a nonsteroidal anti-inflammatory drug NSAID. This medicine works by reducing substances in the body that cause pain and inflammation. Diclofenac is used to treat mild to moderate pain, or signs and symptoms of osteoarthritis or rheumatoid arthritis. Voltaren is also indicated for the treatment of ankylosing spondylitis. The Cataflam brand of this medicine is also used to treat menstrual cramps. Diclofenac powder Cambia is used to treat a migraine headache attack. Cambia will only treat a headache that has already begun. It will not prevent headaches or reduce the number of attacks. Warnings You should not use diclofenac if you have a history of allergic reaction to aspirin or NSAIDs non-steroidal anti-inflammatory drugs. Diclofenac can increase your risk of fatal heart attack or stroke, especially if you use it long term or take high doses, or if you have heart disease. Do not use this medicine just before or after heart bypass surgery coronary artery bypass graft, or CABG. Diclofenac may also cause stomach or intestinal bleeding, which can be fatal. These conditions can occur without warning while you are using this medicine, especially in older adults. Before taking this medicine Diclofenac can increase your risk of fatal heart attack or stroke, even if you don't have any risk factors. Do not use this medicine just before or after heart bypass surgery coronary artery bypass graft, or CABG. Diclofenac may also cause stomach or intestinal bleeding, which can be fatal. These conditions can occur without warning while you are using this medicine, especially in older adults. You should not use diclofenac if you are allergic to it, or if you have ever had an asthma attack or severe allergic reaction after taking aspirin or an NSAID. Do not use Cambia to treat a cluster headache. Do not use Zipsor if you are allergic to beef or beef protein. To make sure this medicine is safe for you, tell your doctor if you have heart disease, high blood pressure; ulcers or bleeding in your stomach; asthma; liver or kidney disease; or if you smoke. Diclofenac can affect ovulation and it may be harder to get pregnant while you are using this medicine. If you are pregnant, you should not take diclofenac unless your doctor tells you to. Taking a NSAID during the last 20 weeks of pregnancy can cause serious heart or kidney problems in the unborn baby and possible complications with your pregnancy. It may not be safe to breastfeed while using this medicine. Ask your doctor about any risk. Diclofenac is not approved for use by anyone younger than 18 years old. How should I take diclofenac? Take diclofenac exactly as prescribed by your doctor. Follow the directions on your prescription label and read all medication guides. Your doctor may occasionally change your dose. Use the lowest dose that is effective in treating your condition. Different brands of diclofenac contain different amounts of diclofenac, and may have different uses. If you switch brands, your dose needs may change. Follow your doctor's instructions about how much medicine to take. Ask your pharmacist if you have any questions about the brand you receive at the pharmacy. Swallow the tablet whole and do not crush, chew, or break it. Take Zorvolex on an empty stomach, at least 1 hour before or 2 hours after a meal. Dissolve the powder form of this medicine Cambia with 1 to 2 ounces of water. Do not use any other type of liquid. Stir this mixture and drink all of it right away. Cambia works best if you take it on an empty stomach. Call your doctor if your headache does not completely go away after taking Cambia. If you use diclofenac long-term, you may need frequent medical tests. Store at room temperature away from moisture and heat. Keep the bottle tightly closed when not in use. Dosing information Usual Adult Dose for Osteoarthritis Diclofenac free acid capsules 35 mg orally 3 times a day Diclofenac potassium immediate-release tablets 50 mg orally 2 or 3 times a day Diclofenac sodium enteric-coated tablets 50 mg orally 2 or 3 times a day or 75 mg orally 2 times a day Maximum dose 150 mg daily Diclofenac sodium extended-release tablets 100 mg orally once a day Use For the relief of signs and symptoms of osteoarthritis. Usual Adult Dose for Ankylosing Spondylitis Diclofenac sodium enteric-coated and delayed-release tablets 25 mg orally 4 times a day. An additional 25 mg dose may be administered at bedtime, if necessary Maximum dose 125 mg per day Use For acute or long-term use in the relief of signs and symptoms of ankylosing spondylitis. Usual Adult Dose for Dysmenorrhea Diclofenac potassium immediate-release tablets 50 mg orally 3 times a day Comments An initial dose of 100 mg orally followed by 50 mg oral doses may provide better relief for some patients; initiate treatment upon appearance of the first symptoms and continue for a few days. Use For the relief of signs and symptoms of primary dysmenorrhea. Usual Adult Dose for Rheumatoid Arthritis Diclofenac potassium immediate-release tablets 50 mg orally 3 or 4 times a day Diclofenac sodium enteric-coated and delayed-release tablets 50 mg orally 3 to 4 times a day or 75 mg orally twice a day Maximum dose 225 mg daily Diclofenac sodium extended-release tablets 100 mg orally once a day Maximum dose 100 mg orally 2 times a day; this would be for the rare patient in whom the benefits outweigh the clinical risks. For the relief of signs and symptoms of rheumatoid arthritis Usual Adult Dose for Migraine Diclofenac potassium for oral solution packets 50 mg 1 packet orally once Comments This drug is not indicated for the prophylactic therapy of migraine or for use in cluster headaches; the safety and efficacy of a second dose has not been established. Use For acute treatment of migraine with or without aura. Usual Adult Dose for Pain Oral Diclofenac potassium liquid-filled capsules 25 mg orally 4 times a day Diclofenac free acid capsules 18 mg or 35 mg orally 3 times a day Diclofenac potassium immediate-release tablets 50 mg orally 3 times a day; an initial dose of 100 mg orally followed by 50 mg oral doses may provide better relief in some patients. Parenteral mg IV bolus over 15 seconds every 6 hours as needed for pain Maximum Dose 150 mg per day Comment Patients should be well hydrated prior to IV administration of this drug in order to reduce the risk of adverse renal reactions. Uses For the management of mild to moderate acute pain oral, IV and moderate to severe pain alone or in combination with opioid analgesics IV. What happens if I miss a dose? Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose. What happens if I overdose? Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. What to avoid Avoid drinking alcohol. It may increase your risk of stomach bleeding. Avoid taking aspirin or other NSAIDs unless your doctor tells you to. Ask a doctor or pharmacist before using other medicines for pain, fever, swelling, or cold/flu symptoms. They may contain ingredients similar to diclofenac such as aspirin, ibuprofen, ketoprofen, or naproxen. Diclofenac side effects Get emergency medical help if you have signs of an allergic reaction to diclofenac hives, difficult breathing, swelling in your face or throat or a severe skin reaction fever, sore throat, burning eyes, skin pain, red or purple skin rash with blistering and peeling. Stop using diclofenac and seek medical treatment if you have a serious drug reaction that can affect many parts of your body. Symptoms may include skin rash, fever, swollen glands, muscle aches, severe weakness, unusual bruising, or yellowing of your skin or eyes. Get emergency medical help if you have signs of a heart attack or stroke chest pain spreading to your jaw or shoulder, sudden numbness or weakness on one side of the body, slurred speech, feeling short of breath. Stop using this medicine and call your doctor at once if you have the first sign of any skin rash, no matter how mild; flu-like symptoms; heart problems - swelling, rapid weight gain, feeling short of breath; kidney problems - little or no urinating, painful or difficult urination, swelling in your arms or legs, feeling tired or short of breath; liver problems - nausea, diarrhea, stomach pain upper right side, tiredness, itching, dark urine, jaundice yellowing of the skin or eyes; or signs of stomach bleeding - bloody or tarry stools, coughing up blood or vomit that looks like coffee grounds. Common diclofenac side effects may include indigestion, gas, nausea, vomiting, stomach pain; diarrhea, constipation; headache, dizziness, drowsiness; abnormal lab tests; itching, sweating; stuffy nose; increased blood pressure; or swelling or pain in your arms or legs. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. What other drugs will affect diclofenac? Ask your doctor before using diclofenac if you take an antidepressant. Taking certain antidepressants with an NSAID may cause you to bruise or bleed easily. Tell your doctor about all your other medicines, especially heart or blood pressure medication, including a diuretic or "water pill"; other forms of diclofenac Arthrotec, Flector, Pennsaid, Solaraze, Voltaren Gel; a blood thinner - warfarin, Coumadin, Jantoven; or other NSAIDs - aspirin, ibuprofen Advil, Motrin, naproxen Aleve, celecoxib Celebrex, indomethacin, meloxicam, and others. This list is not complete. Other drugs may interact with diclofenac, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here. Popular FAQ There is no known drug interaction between methocarbamol and non-steroidal anti-inflammatory drugs NSAIDs such as diclofenac. You may take methocarbamol and diclofenac together. Because it may cause drowsiness or dizziness, methocarbamol interacts with other drugs that have similar effects, such as alcohol and drugs that treat sleep disorders. Can I take ibuprofen with blood pressure medications? You need to be careful when taking ibuprofen with blood pressure medicines because the combination can also cause serious damage to your kidneys, particularly if you are also taking a diuretic water pill. In addition, ibuprofen can reduce the blood pressure lowering effect of your blood pressure medication. People who take blood pressure medications called ACE inhibitors or ARBs and diuretics have an increased risk of kidney damage, which can be compounded by also taking an NSAID, such as ibuprofen, particularly in high doses. Continue reading More FAQ Which painkiller should you use? Why is diclofenac prescription only but ibuprofen is OTC? Can NSAIDs be used to treat a COVID-19 fever? View more FAQ Further information Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use diclofenac only for the indication prescribed..Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. Medical Disclaimer Copyright 1996-2023 Cerner Multum, Inc. Version Lafen Kemasan Dos isi 10 strip 10 tablet salut enterik No. Reg. DKL 1106313515A1 Komposisi Tiap tablet salut enterik mengandung, Diclofenac Sodium 50 mg Indikasi Sindrome nyeri pada kolumna vertebralis. Artritis rematik, osteoartritis, spondilitis ankilosa. 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